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Renee Zellweger, Rob Lowe and Kristin Chenoweth have teamed up to front a new cancer awareness campaign.

The Hollywood stars have filmed an commercial for the Stand Up To Cancer organization to raise the profile of the disease and encourage the public to fight back.

Zellweger says, "It's up to me, it's up to you, it's up to all of us," while Lowe adds: "It's up to sons and daughters."

The ad, in which the stars write slogans on a white wall, will also feature Alicia Keys and Justin Timberlake as part of the campaign.