Emma Stone didn't have to look too far for inspiration for her The Amazing Spider-Man character Gwen Stacy - her aunt is a pioneering scientist who introduced the chicken pox vaccine to America.
Peter Parker's girlfriend is a science expert in the Spider-Man films and so Stone turned to her boffin aunt to perfect her character.
She tells WENN, "My aunt is a really brilliant scientist and so I got to know about that aspect of my family a little bit more.
"She works on vaccines, so she worked on the Gardasil vaccine, which guards against cervical cancer, and she brought the chicken pox vaccine to America from Germany. And she's working on a MRSA (Methicillin-resistant Staphylococcus aureus) vaccine now. She's pretty bad a**! She's very straightforward and one of the most direct people I've ever known."
And director Marc Webb also turned to a scientific family member to perfect the film's laboratory sets.
He explains, "My mom worked in a lab for her entire career. I grew up in Wisconsin, next to the university, and my brother is an engineer, so I spent so much of my life at lunchtime sitting with my mom while she's drawing blood; just being in the laboratory. I even remember the very specific smells that come from laboratories."