She's set to step behind the camera again to be boss on the set of rockers Best Coast's video for their new single Our Deal.
The promo will star Kick-Ass actress Moretz and iCarly sensation Miranda Cosgrove.
Best Coast's frontwoman Bethany Cosentino tells Rolling Stone, "I met Drew Barrymore after a show in L.A. and we ended up talking about how we could work together. So she's going to direct a video and Miranda Cosgrove, Chloe Moretz and (comic) Donald Glover are all going to be in it. It's got a very cool concept, which Drew came up with."